pbpk model commercial software gastroplus (Simulations Plus Inc)
Structured Review

Pbpk Model Commercial Software Gastroplus, supplied by Simulations Plus Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/pbpk+model+commercial+software+gastroplus/pmc08779920-90-12-19?v=Simulations+Plus+Inc
Average 90 stars, based on 1 article reviews
Images
1) Product Images from "In Vitro and In Vivo Bioequivalence Study of 3D-Printed Instant-Dissolving Levetiracetam Tablets and Subsequent Personalized Dosing for Chinese Children Based on Physiological Pharmacokinetic Modeling"
Article Title: In Vitro and In Vivo Bioequivalence Study of 3D-Printed Instant-Dissolving Levetiracetam Tablets and Subsequent Personalized Dosing for Chinese Children Based on Physiological Pharmacokinetic Modeling
Journal: Pharmaceutics
doi: 10.3390/pharmaceutics14010020
Figure Legend Snippet: Validation results of the PBPK model with different dosing regimens (the solid line is the prediction result and the dashed line is the validation result).
Techniques Used: Biomarker Discovery
Figure Legend Snippet: Prediction results of the oral LEV PBPK model in the Chinese pediatric population.
Techniques Used:
Figure Legend Snippet: Predicted results of the oral PBPK model in 4-year-old Chinese children. ( A ) 177.8 mg, q 12 h; ( B ) 300 mg + 200 mg, q 12 h.
Techniques Used:
Figure Legend Snippet: Prediction results of the 280 mg + 222.6 mg oral LEV-PBPK model in 6-year-old Chinese children. ( A ) Seven-day drug–time curve after normal administration; ( B ) 300 mg drug–time curve after remediation of a missed dose; ( C ) 275 mg drug–time curve after a missed dose; ( D ) 350 mg drug–time curve after remediation of a missed dose.
Techniques Used: